Applying Flow Chemistry: Methods, Materials, and Multistep Synthesis
The Journal of Organic Chemistry2013Vol. 78(13), pp. 6384–6389
Citations Over TimeTop 1% of 2013 papers
Abstract
The synthesis of complex molecules requires control over both chemical reactivity and reaction conditions. While reactivity drives the majority of chemical discovery, advances in reaction condition control have accelerated method development/discovery. Recent tools include automated synthesizers and flow reactors. In this Synopsis, we describe how flow reactors have enabled chemical advances in our groups in the areas of single-stage reactions, materials synthesis, and multistep reactions. In each section, we detail the lessons learned and propose future directions.
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