Catalytic sp3 C–H Oxidation of Peptides and Their Analogues by Radical Cation Salts: From Glycine Amides to Quinolines
The Journal of Organic Chemistry2013Vol. 78(18), pp. 9450–9456
Citations Over TimeTop 10% of 2013 papers
Abstract
A catalytic α-sp(3) C-H oxidation of peptides and glycine amides was achieved under radical cation salt catalysis in the presence of O2, producing a series of substituted quinolines. The scope of this reaction shows good functional group tolerance and high efficiency of the oxidative functionalization.
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