Palladium-Catalyzed Carbonylative Cross-Coupling with Imines: A Multicomponent Synthesis of Imidazolones
The Journal of Organic Chemistry2007Vol. 73(3), pp. 1135–1138
Citations Over TimeTop 20% of 2007 papers
Abstract
The palladium-catalyzed coupling of imines, chloroformates, organotin reagents, and carbon monoxide leads to the one-pot formation of ketocarbamates in good yields. These products can further be converted to highly substituted imidazolones via a cyclocondensation reaction. Overall, this methodology provides an alternative approach to imidazolones from five simple and readily available building blocks via a one-pot, multicomponent process.
Related Papers
- → Evolution of Carbonylation Catalysis: No Need for Carbon Monoxide(2004)578 cited
- → CO-Transfer Carbonylation Reactions. A Catalytic Pauson−Khand-Type Reaction of Enynes with Aldehydes as a Source of Carbon Monoxide(2002)249 cited
- → Catalytic Carbonylation Methods without the Direct Use of Carbon Monoxide(2004)5 cited
- → Double Carbonylation of Organohalogen Compounds Catalyzed by Polymer-Bound Palladium Complexes(1987)4 cited
- → Formation of Nickelacycles and Reaction with Carbon Monoxide(2019)2 cited