Synthesis of Quinolines from 3-Formylchromone
The Journal of Organic Chemistry2008Vol. 73(15), pp. 6010–6013
Citations Over TimeTop 12% of 2008 papers
Andrey S. Plaskon, Sergey V. Ryabukhin, Dmitriy M. Volochnyuk, Konstantin S. Gavrilenko, Alexander Shivanyuk, Andrey A. Tolmachev
Abstract
A facile and versatile procedure for the synthesis of 3-(2-hydroxybenzoyl)quinolines and 7H-chromeno[3,2-c]quinolin-7-ones was elaborated on the basis of TMSCl-mediated recyclization of 3-formylchromone with various anilines. Limitations and scope of this methodology were established, and a possible mechanism for the heterocyclizations was proposed.
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