Vilsmeier Reaction of Enaminones: Efficient Synthesis of Halogenated Pyridin-2(1H)-ones
The Journal of Organic Chemistry2008Vol. 73(23), pp. 9504–9507
Citations Over TimeTop 10% of 2008 papers
Abstract
A facile and efficient one-pot synthesis of halogenated pyridin-2(1H)-ones from a series of readily available enaminones under Vilsmeier conditions is described, and a mechanism involving sequential halogenation, formylation, and intramolecular nucleophilic cyclization is proposed.
Related Papers
- → A new procedure for formylation of less active aromatics(1990)53 cited
- → Synthetic Utility of the Vilsmeier–Haack Reagent in Organic Synthesis(2023)8 cited
- → Oxidation‐Induced para‐Selective Formylation of N,N‐Substituted Aniline(2018)3 cited
- → Vilsmeier formylation of vinylcyclopropanes: 1. Formylation of thujopsene(1973)13 cited
- → ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ(2024)