HIV-1 Protease Inhibitors Based on Acyclic Carbohydrates
The Journal of Organic Chemistry1998Vol. 63(15), pp. 4898–4906
Citations Over TimeTop 12% of 1998 papers
Guido Zuccarello, Abderrahim Bouzide, Ingemar Kvarnström, Gunilla Niklasson, S. Svensson, Magnus Brisander, Helena Danielsson, Ulrika Nillroth, Anders Karlén, Anders Hallberg, Björn Classon, Bertil Samuelsson
Abstract
A series of acyclic C2-symmetric HIV protease inhibitors readily accessible from d-mannitol have been developed. Several of the compounds synthesized showed significant in vitro activity against HIV-1 protease.
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