Palau'amine and Its Congeners: A Family of Bioactive Bisguanidines from the Marine Sponge Stylotella aurantium1
The Journal of Organic Chemistry1998Vol. 63(10), pp. 3281–3286
Citations Over TimeTop 10% of 1998 papers
Abstract
The strongly cytotoxic, antibiotic, and immunosuppressive palau'amine was isolated from the Belau sponge Stylotella aurantium, along with less active 4-bromo and 4,5-dibromo derivatives. Three corresponding isomeric compounds, all less active, were also isolated, and full details of the isolation and all structure proofs are provided.
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