Properties of Spanning Water Networks at Protein Surfaces
Citations Over TimeTop 10% of 2005 papers
Abstract
The formation of a spanning two-dimensional hydrogen-bonded water network at the surface of proteins via a percolation transition enables their biological function. We show in detail how the spanning (percolating) water network appears at the surfaces of model hydrophilic spheres and at the surface of a single protein (lysozyme) molecule. We have found essential correlations of the linear extension, radius of gyration, and position of the center of mass of the largest water cluster with its size. The specific two-peak structure of the probability distribution of the largest cluster size allowed us to study various properties separately for spanning and nonspanning largest clusters. The radius of gyration of the spanning cluster always exceeds the radii of the spheres or the effective radius of the protein. Any spanning cluster envelops essentially more than half of the surface area. The temporal decay of the spanning networks shows a stretched exponential character. Their average lifetime at the percolation threshold is about the lifetime of a water-water hydrogen bond.
Related Papers
- → A solution of Chartrand's problem on spanning trees(1984)8 cited
- → Pinning Control on Directed Complex Network via Identifying Spanning Trees(2012)
- → Transformations on Spanning Trees(1978)
- Counting of Spanning Trees in Complete Graph K_p of Even Order(2009)
- → Cofiltrations of spanning trees in multiparameter persistent homology(2023)