Self-Assembly Process of Peptide Amphiphile Worm-Like Micelles
Citations Over TimeTop 12% of 2011 papers
Abstract
Peptide amphiphile molecules (PA) are remarkably versatile and useful as building blocks for construction of complex supramolecular structures in a bottom-up fashion. Worm-like micelles of PA have been demonstrated to have successful application to creation of synthetic extracellular matrix materials for tissue engineering and regenerative medicine. However, the pathway of the self-assembly process of the PA worm-like micelle has not been fully characterized or understood. This work analyzes the self-assembly process leading to worm-like micelle formation in our designed PA with small-angle neutron scattering and atomic force microscopy. The experimental results demonstrate the existence of transient spherical micelles in the early stage of the process and subsequent micelle chain elongation by attachment of spherical micelles to the end of growing cylindrical micelles to form worm-like micelles in a process mimicking chain-growth polymerization.
Related Papers
- → Helical Porous Protein Mimics Self-Assembled from Amphiphilic Dendritic Dipeptides*(2005)50 cited
- → Bolaform Supramolecular Amphiphiles as a Novel Concept for the Buildup of Surface-Imprinted Films(2011)29 cited
- → CO2-Enhanced Bola-Type Supramolecular Amphiphile Constructed from Pillar[5]arene-Based Host–Guest Recognition(2018)19 cited
- → Gemini-Type Supramolecular Amphiphile Based on a Water-Soluble Pillar[5]arene and an Azastilbene Guest and Its Application in Stimuli-Responsive Self-Assemblies(2019)13 cited
- → Controlled Supramolecular Assembly of Gold (III) Amphiphiles in Aqueous Media(2022)4 cited