Functionalized Plasmonic−Fluorescent Nanoparticles for Imaging and Detection
Citations Over TimeTop 10% of 2009 papers
Abstract
Plasmonic−fluorescent composite nanoparticles are considered as unique, multifunctional nanoprobes for plasmon- and fluorescence-based imaging and detection. However, their synthesis is challenging due to fluorescence quenching of the fluorophore by plasmonic particles and most of the successful methods produce composite particles of large size (diameter > 50 nm), which limit their wider applications. Here we report 20−30 nm diameter plasmonic−fluorescent composite nanoparticles with reasonable fluorescence quantum yield (12−16%). These particles are composed of 3−6 nm diameter Au/Ag cores and fluorescein-incorporated polymeric shells. They have high water solubility, good colloidal stability, stable fluorescence properties, and are amenable in deriving various functional nanoprobes. Different functional nanoprobes are derived from these composites and successfully used for fluorescence-based cell labeling as well as plasmon-based detection applications.
Related Papers
- → Fluorescence-Quenching Phenomenon by Photoinduced Electron Transfer between a Fluorescent Dye and a Nucleotide Base(2001)352 cited
- → Environment-Sensitive Fluorophore Emitting in Protic Environments(2006)91 cited
- → In vivo fluorescence imaging for Cu2+ in live mice by a new NIR fluorescent sensor(2016)52 cited
- → Absolute quantum yield measurements of fluorescent proteins using a plasmonic nanocavity(2020)30 cited
- → A Comprehensive Studies of an Indolizine-Based Seoul-Fluor System(2018)