Orientational Changes of Amphotericin B in Langmuir Monolayers Observed by Brewster Angle Microscopy

Citations Over TimeTop 10% of 2001 papers

Abstract

The morphology of amphotericin B monolayers spread at the air/water interface was investigated at the microscopic level with a Brewster angle microscope. The images were recorded simultaneously with the surface pressure (π)/area (A) isotherms. The transformation from the domain-like structure to homogeneous solid phase was observed upon monolayer compression. Quantitative analysis was made from the measurements of relative reflectivity during monolayer compression/decompression. A 3-fold increase in relative monolayer thickness throughout the compression from the expanded to a condensed state is observed and related to orientational changes of the monolayer molecules from a horizontal to a vertical position.

Related Papers

• → Morphological and Structural Characteristics of Monoglyceride Monolayers at the Air−Water Interface Observed by Brewster Angle Microscopy(1999)123 cited
• → Langmuir monolayers from perfluorobutyl-n-eicosane(2004)14 cited
• → Chiral discrimination in Langmuir monolayers of N-eicosanoylproline methyl ester(1995)10 cited
• → β-Carotene does not form a true Langmuir monolayer at the air/water interface(2011)6 cited
• → Silver n-Octadecanethiolate Langmuir Monolayers Mimicking Self-Assembled Monolayers on Silver(1996)11 cited