Self-Assembly of Poly(ethylene glycol)−Poly(alkyl phosphonate) Terpolymers on Titanium Oxide Surfaces: Synthesis, Interface Characterization, Investigation of Nonfouling Properties, and Long-Term Stability

Citations Over TimeTop 10% of 2009 papers

Abstract

This contribution deals with the self-assembling of a terpolymer on titanium oxide (TiO(2)) surface. The polymer structure was obtained by polymerization of different methacrylates, i.e., alkyl-phosphonated, butyl and PEG methacrylate, in the presence of a chain transfer agent. The resulting PEG-poly(alkyl phosphonate) material, characterized mainly by SEC and NMR, self-organized at the interface of TiO(2). AR-XPS demonstrated the binding of phosphonate groups to TiO(2) substrate and the formation of a PEG-brush layer at the outermost part of the system. The stability of this terpolymer adlayer, after exposure to solutions of pH 2, 7.4, and 9 up to 3 weeks, was evaluated quantitatively by XPS and ellipsometry. We demonstrated an overall stability improvements of this coating against desorption in contact with aqueous solutions in comparison with reference self-assembly systems. Finally, the PEG-terpolymer adlayer proved to impart to TiO(2) substrate antifouling properties when exposed to full blood serum.

Related Papers

• → Sensitive and Quantitative Detection of Anti-Poly(ethylene glycol) (PEG) Antibodies by Methoxy-PEG-Coated Surface Plasmon Resonance Sensors(2017)33 cited
• → Preparation of a novel series of phosphonate norstatine renin inhibitors(1994)34 cited
• → Facile installation of the phosphonate and (α,α-difluoromethyl)phosphonate functionalities equipped with benzyl protection(1999)37 cited
• → Microwave‐Assisted Single‐Step Synthesis of Poly(alkylene hydrogen phosphonate)s by Transesterification of Dimethyl Hydrogen Phosphonate with Poly(ethylene glycol)(2005)32 cited
• → Simple GLC Determination of Ethylene Oxide and Its Reaction Products in Drugs and Formulations(1977)12 cited