Hydrophilic/Hydrophobic Patterned Surfaces as Templates for DNA Arrays
Langmuir2000Vol. 16(18), pp. 7223–7228
Citations Over TimeTop 10% of 2000 papers
Abstract
Addressable DNA arrays are created by photopatterning self-assembled monolayers to form hydrophilic and hydrophobic regions on a gold surface. The hydrophilic regions aid to contain small volumes of different DNA solutions placed on them using an automated pin-tool loading strategy. The method allows for efficient attachment, manipulation, and hybridization of pure DNA strands on the surface.
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