Synthesis of Glyconanospheres Containing Luminescent CdSe−ZnS Quantum Dots
Citations Over TimeTop 10% of 2003 papers
Abstract
Negatively charged luminescent CdSe−ZnS quantum dots (QDs) were successfully incorporated into novel luminescent glyconanopsheres averaging 190 nm in diameter through electrostatic interactions with carboxymethyldextran (CM-dextran) and polylysine. In addition to electrostatic attraction between the negatively charged dextran, the negatively charged CdSe−ZnS QDs, and the positively charged polylysine, covalent amide bonds were introduced to cross link the QDs with the polysaccharide matrix to further stabilize the nanospheres. The dextran residues on the surface of the nanospheres show high affinity toward the glucose binding protein-Concanavalin A (Con A). As a result, these luminescent CdSe−ZnS QD incorporated glyconanospheres are a useful tool for studying carbohydrate−protein interactions that are critical steps in bacterial and viral infection.
Related Papers
- → Effect of the ordered interfacial water layer in protein complex formation: A nonlocal electrostatic approach(2010)21 cited
- → Studies on electrostatic interactions within model nano-confined aqueous environments of different chemical nature(2017)9 cited
- → The effect of electrostatics on factor H function and related pathologies(2011)13 cited
- → Mathematical simulation of interactions of protein molecules and prediction of their reactivity(2016)6 cited
- Effects of Electrostatic and Hydrophobic Interaction on the Stability of SARS Coronavirus 3CL Proteinase Dimer(2005)