Gold Nanocages: Bioconjugation and Their Potential Use as Optical Imaging Contrast Agents
Citations Over TimeTop 1% of 2005 papers
Abstract
Gold nanocages of <40 nm in dimension have been synthesized using the galvanic replacement reaction between Ag nanocubes and HAuCl4 in an aqueous solution. By controlling the molar ratio between Ag and HAuCl4, the gold nanocages could be tuned to display surface plasmon resonance peaks around 800 nm, a wavelength commonly used in optical coherence tomography (OCT) imaging. OCT measurements on phantom samples indicate that these gold nanocages have a moderate scattering cross-section of ∼8.10 × 10-16 m2 but a very large absorption cross-section of ∼7.26 × 10-15 m2, suggesting their potential use as a new class of contrast agents for optical imaging. When bioconjugated with antibodies, the gold nanocages have also been demonstrated for specific targeting of breast cancer cells.
Related Papers
- → Self-Assembly of Responsive Multilayered DNA Nanocages(2015)101 cited
- → Chemically coupled NiCoS/C nanocages as efficient electrocatalysts for nitrogen reduction reactions(2019)67 cited
- → MB11N12 (M = Fe–Zn) Nanocages for Cyanogen Chloride Detection: A DFT Study(2023)15 cited
- → Hollow Boron Nitride (BN) Nanocages and BN‐Nanocage‐Encapsulated Nanocrystals(2004)59 cited
- → Thermodynamic Stability of Discrete Fully Coordinated SiO2 Spherical and Elongated Nanocages(2004)53 cited