Interaction of Polyelectrolytes and Their Composites with Living Cells
Nano Letters2005Vol. 5(12), pp. 2605–2612
Citations Over TimeTop 10% of 2005 papers
Munish Chanana, Alessandra Gliozzi, Alberto Diaspro, Irina Chodnevskaja, Sabine Huewel, Vasiliy Moskalenko, K. Ulrichs, Hans-Joachim Galla, Silke Krol
Abstract
Since the layer-wise polyelectrolyte deposition offers the opportunity to modify surfaces for biomedical applications, interactions and toxicity between polyelectrolytes and living cells become interesting. The aim of the present work is to determine the different factors such as contact area, charge, and transplantation site that influence the cell reaction to a specific polymer. We found that toxicity is influenced by all these factors and cannot be tested easily in a model.
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