Four New Triterpenoid Saponins from Conyza blinii

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Abstract

Three new bisdesmosidic saponins named conyzasaponins A, B, and C (1−3) and one new monodesmosidic saponin, conyzasaponin G (4), were isolated from the aerial parts of Conyza blinii. Their structures were elucidated on the basis of extensive NMR (DEPT, DQF-COSY, HOHAHA, HMQC, HMBC, and NOESY) and MS studies. Compounds 1−3 share a common prosapogenin, bayogenin 3-O-β-d-xylopyranosyl-(1→3)-β-d-glucopyranoside, which is identical with conyzasaponin G (4), and differ in the structures of the ester-linked sugar moieties at C-28. Conyzasaponin A (1) is the 28-O-β-d-apiofuranosyl-(1→3)-β-d-xylopyranosyl-(1→4)-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranosyl ester, conyzasaponin B (2), the 28-O-β-d-apiofurano- syl-(1→3)-β-d-xylopyranosyl-(1→4)-[α-l-arabinopyranosyl-(1→3)]-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranosyl ester, and conyzasaponin C (3), the 28-O-α-l-rhamnopyranosyl-(1→3)-β-d-xylopyranosyl-(1→4)-[β-d-apiofuranosyl-(1→3)]-α-l-rhamnopyranosyl-(1→2)-α-l-arabinopyranosyl ester of the prosapogenin, respectively.

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