Bombardolides: New Antifungal and Antibacterial γ-Lactones from the Coprophilous Fungus Bombardioidea anartia
Journal of Natural Products2001Vol. 64(6), pp. 809–812
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Abstract
Chemical studies of organic extracts from cultures of the coprophilous fungus Bombardioidea anartia have led to the discovery of bombardolides A−D (1−4), a series of new antifungal and antibacterial metabolites. Three of these metabolites (1−3) were obtained as inseparable pairs of geometric isomers. A new 3-substituted phenol (5) and the known compound asterriquinone B4 were also encountered. The structures of compounds 1−5 were determined by analysis of NMR and MS data.
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