Isotsaokoin, an Antifungal Agent from Amomum tsao-ko
Journal of Natural Products2004Vol. 67(5), pp. 889–891
Citations Over Time
Abstract
Bioassay-guided purification of a methanol extract from Amomum tsao-ko led to the isolation of the bicyclic nonane isotsaokoin (1) as the major active principle, an isomer of the previously reported tsaokoin (2). The stereochemical relationship of 1 and 2 was investigated by NOE experiments and Mosher ester derivatization. Compound 1 showed antifungal activity against Trycophyton mentagrophytes.
Related Papers
- → 1,9-seco-Bicyclic Polyprenylated Acylphloroglucinols from Hypericum uralum(2015)28 cited
- → Dancing of the Second Aromatic Residue around the 6,8-Diazabicyclo[3.2.2]nonane Framework: Influence on σ Receptor Affinity and Cytotoxicity(2009)37 cited
- → Conformationally Constrained κ Receptor Agonists: Stereoselective Synthesis and Pharmacological Evaluation of 6,8-Diazabicyclo[3.2.2]nonane Derivatives†(2010)27 cited
- → On the Resolution of Chiral Substrates by a retro‐Claisenase Enzyme: Biotransformations of Heteroannular Bicyclic β‐Diketones by 6‐Oxocamphor Hydrolase(2007)12 cited
- → Synthesis and Dopamine Transporter Affinity of 2-(Methoxycarbonyl)-9-methyl-3-phenyl-9-azabicyclo[3.3.1]nonane Derivatives(1996)17 cited