Bacterial Biofilm Inhibitors from Diospyros dendo
Journal of Natural Products2006Vol. 69(1), pp. 118–120
Citations Over TimeTop 11% of 2006 papers
Jin‐Feng Hu, Eliane Garo, Matt G. Goering, Mark Pasmore, Hye‐Dong Yoo, T. E. B Esser, Jennifer Sestrich, Peadar Cremin, Grayson Hough, Peter Perrone, Yin-Shi L. Lee, Ngoc-Tram Le, Mark O’Neil-Johnson, J. William Costerton, Gary R. Eldridge
Abstract
One new (1) and four known (2-5) ursene triterpenes with potent inhibition of the formation of the bacterial biofilm Pseudomonas aeruginosa PA01 were obtained from Diospyros dendo using a high-throughput natural products chemistry procedure. These compounds were isolated as mass-limited samples. The miniaturization of the structure elucidation and dereplication was performed primarily utilizing a capillary-scale NMR probe.
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