Antiviral Alkaloids Produced by the Mangrove-Derived Fungus Cladosporium sp. PJX-41
Journal of Natural Products2013Vol. 76(6), pp. 1133–1140
Citations Over TimeTop 10% of 2013 papers
Abstract
Six new indole alkaloids including five new glyantrypine derivatives (1, 2a, 2b, 3, 4) and a new pyrazinoquinazoline derivative (5), together with eight known alkaloids (6-13), were isolated from the culture of the mangrove-derived fungus Cladosporium sp. PJX-41. Their structures were elucidated primarily by spectroscopic and physical data. The absolute configurations of compounds 1-9 were established on the basis of CD, NOESY data, and single-crystal X-ray diffraction analysis. Compounds 2b, 5, 7-9, and 11 exhibited significant activities against influenza virus A (H1N1), with IC50 values of 82-89 μM.
Related Papers
- → Differentiation between true mangroves and mangrove associates based on leaf traits and salt contents(2010)134 cited
- RELATIVE IMPORTANCE OF MANGROVES AS FEEDING HABITATS FOR FISHES: A COMPARISON BETWEEN MANGROVE HABITATS WITH DIFFERENT SETTINGS(2007)
- → True mangrove species of Sundarbans Delta, West Bengal, eastern India(2014)70 cited
- Relative importance of mangroves as feeding habitat for juvenile fish: a comparative study on mangrove habitats with different settings(2007)
- Studies on Area Assessment under Mangroves of Raigad District, Maharashtra, India(2017)