Limonoids from Aphanamixis polystachya and Their Antifeedant Activity
Journal of Natural Products2013Vol. 77(3), pp. 472–482
Citations Over Time
Jieyun Cai, Duo‐Zhi Chen, Shi‐Hong Luo, Ning‐Chuan Kong, Yu Zhang, Ying‐Tong Di, Qıang Zhang, Juan Hua, Shu-Xi Jing, Shun‐Lin Li, Sheng‐Hong Li, Xiao‐Jiang Hao, Hongping He
Abstract
Eight new aphanamixoid-type aphanamixoids (C-J, 1-8) and six new prieurianin-type limonoids, aphanamixoids K-P (9-14), along with 10 known terpenoids were isolated from Aphanamixis polystachya, and their structures were established by spectroscopic data analysis. Among the new limonoids, 13 compounds exhibited antifeedant activity against the generalist Helicoverpa armigera, a plant-feeding insect, at various concentration levels. In particular, compounds 1, 4, and 5 showed potent activities with EC50 values of 0.017, 0.008, and 0.012 μmol/cm(2), respectively. On the basis of a preliminary structure-activity relationship analysis, some potential active sites in the aphanamixoid-type limonoid molecules are proposed.
Related Papers
- → The Advances in the Limonoid Chemistry of the Meliaceae Family(2011)121 cited
- → The limonoid chemistry of the genus Khaya (meliaceae)(1971)61 cited
- → Ceramicine A and walsogyne A, novel limonoids from two species of Meliaceae(2008)52 cited
- → A novel limonoid from the seeds of Chisocheton siamensis(2008)19 cited
- → Quivisianthone, an evodulone limonoid from the Madagascan Meliaceae Quivisia papinae(2003)12 cited