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Alectosarmentin, a New Antimicrobial Dibenzofuranoid Lactol from the Lichen, Alectoria sarmentosa
Journal of Natural Products1994Vol. 57(7), pp. 934–938
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Rao Gollapudi, Hanumaiah Telikepalli, Hanuman B. Jampani, Youssef Wissa Mirhom, Steven D. Drake, Kesava Rao Bhattiprolu, David Vander Velde, Lester A. Mitscher
Abstract
From the alcoholic extract of the lichen Alectoria sarmentosa, four compounds showing antimicrobial activity were isolated. Of these, (-)-usnic acid and physodic acid are well known lichen products, 8'-O-ethyl-beta-alectoronic acid [2] is believed to be an artifact formed during isolation and fractionation, and alectosarmentin [1] is a new natural product whose structure was shown, by spectroscopy and chemical transformations, to be that of a dibenzofuranoid lactol. The antimicrobial activity of these substances accounts for the activity of the lichen.
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