Protein Kinase C Inhibitors: Novel Spirosesquiterpene Aldehydes from a Marine Sponge Aka (=Siphonodictyon) coralliphagum

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Abstract

Two novel spirosesquiterpene aldehydes, corallidictyals A [1] and B [2], were isolated as a mixture from the marine sponge Aka (= Siphonodictyon) coralliphagum, and their structures were determined by detailed spectroscopic methods. These compounds were identified in a screen for inhibitors of protein kinase C.

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