Cytotoxic Polyketides from a Marine-derived Fungus Aspergillus glaucus
Journal of Natural Products2008Vol. 71(11), pp. 1837–1842
Citations Over TimeTop 18% of 2008 papers
Abstract
Eight new aromatic polyketides (2, 4-6, 8, 14, 16, and 17) together with eight known analogues (3, 7, 9-13, and 15) were isolated from the marine-derived fungus Aspergillus glaucus. The structures and stereochemistry of the new compounds were elucidated by spectroscopic and chemical methods, and their cytotoxicities were evaluated against the HL-60 and A-549 cell lines.
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