Oxylipins from Dracontium loretense
Journal of Natural Products2009Vol. 72(5), pp. 813–817
Citations Over TimeTop 23% of 2009 papers
Angelyne Benavides, Assunta Napolitano, Carla Bassarello, Virginia Carbone, Patrizia Gazzerro, Anna Maria Malfitano, Paola Saggese, Maurizio Bifulco, Sonia Piacente, Cosimo Pìzza
Abstract
Four novel oxylipins (1-4) were isolated from the n-butanol extract of the corms of Dracontium loretense. Their structures were assigned by 1D and 2D NMR analyses and electrospray ionization multistage ion trap mass spectrometry (ESI-ITMS(n)) data. Relative configurations were assigned on the basis of combined analysis of homonuclear and heteronuclear (2,3)J couplings, along with ROE data. Oxylipin 2 exhibited an immunostimulatory effect on human PBMC proliferation.
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