Harzianic Acid, an Antifungal and Plant Growth Promoting Metabolite from Trichoderma harzianum
Journal of Natural Products2009Vol. 72(11), pp. 2032–2035
Citations Over TimeTop 15% of 2009 papers
Francesco Vinale, Gavin R. Flematti, K. Sivasithamparam, Matteo Lorito, Roberta Marra, Brian W. Skelton, Emilio L. Ghisalberti
Abstract
A Trichoderma harzianum strain, isolated from composted hardwood bark in Western Australia, was found to produce a metabolite with antifungal and plant growth promoting activity. The structure and absolute configuration of the fungal compound, harzianic acid (1), were determined by X-ray diffraction studies. Harzianic acid showed antibiotic activity against Pythium irregulare, Sclerotinia sclerotiorum, and Rhizoctonia solani. A plant growth promotion effect was observed at low concentrations of 1.
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