Halishigamides A−D, New Cytotoxic Oxazole-Containing Metabolites from Okinawan Sponge Halichondria sp.
Journal of Natural Products1997Vol. 60(2), pp. 150–154
Citations Over TimeTop 11% of 1997 papers
Abstract
Four new oxazole-containing compounds, halishigamides A−D (1−4), have been isolated from an Okinawan marine sponge Halichondria sp. and the structures elucidated on the basis of 2D NMR data. Halishigamide A (1) is the first trisoxazole-containing macrolide possessing a primary amino group in the macrolactone ring.
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