A Cyclized Didemnimide Alkaloid from the Caribbean Ascidian Didemnum conchyliatum
Journal of Natural Products1998Vol. 62(2), pp. 389–391
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Abstract
A novel, cyclized alkaloid of the didemnimide class, 5, has been isolated from extracts of the Caribbean ascidian Didemnum conchyliatum. The structure of 5 was assigned using combined spectral methods that emphasized one- and two-dimensional NMR methods. The new alkaloid is the cyclization product of didemnimide A (1) formed via a C-2 indole condensation with the imidazole nitrogen.
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