Pairwise Use of Complexity-Generating Reactions in Diversity-Oriented Organic Synthesis
Organic Letters2000Vol. 2(5), pp. 709–712
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Abstract
[reaction: see text] Two pairs of complexity-generating reactions with an essential product-substrate relationship along a synthetic pathway are demonstrated. This pathway illustrates a key element in a planning algorithm for diversity-oriented synthesis. This element facilitates the efficient synthesis of structurally complex compounds, and it can be integrated with ones that provide structurally diverse compounds.