Palladium-Catalyzed Intermolecular Coupling of Aryl Halides and Amides
Organic Letters2000Vol. 2(8), pp. 1101–1104
Citations Over TimeTop 1% of 2000 papers
Abstract
[formula: see text] The first general intermolecular C-N bond-forming reactions between aryl halides and amides were realized using a palladium catalyst with Xantphos as the ligand. Aryl triflates, carbamates, and sulfonamides are also viable substrates for the amidations, which proceed at 45-110 degrees C with 1-4 mol% of Pd catalyst in 66-99% yields and exhibit good functional group compatibility.
Related Papers
- → Xantphos doped Rh/POPs-PPh3 catalyst for highly selective long-chain olefins hydroformylation: Chemical and DFT insights into Rh location and the roles of Xantphos and PPh3(2017)85 cited
- → Palladium‐Catalyzed Direct Cross‐Coupling of Carboranyllithium with (Hetero)Aryl Halides(2016)30 cited
- → Fast and Easy Halide Exchangein Aryl Halides(2003)11 cited
- → Convergent Synthesis of N,S-bis Glycosylquinolin-2-ones via a Pd-G3-XantPhos Precatalyst Catalysis(2018)9 cited
- → ChemInform Abstract: CONVENIENT SYNTHESIS OF ARYL HALIDES FROM ARYLAMINES VIA TREATMENT OF 1‐ARYL‐3,3‐DIALKYLTRIAZENES WITH TRIMETHYLSILYL HALIDES(1982)