Regioselective Palladium-Catalyzed Arylation of 2-Furaldehyde
Organic Letters2001Vol. 3(11), pp. 1677–1680
Citations Over TimeTop 10% of 2001 papers
Michael S. McClure, Bobby Glover, Ellen McSorley, Alan Millar, Martin H. Osterhout, Frank Roschangar
Abstract
An efficient regioselective method for the direct arylation of 2-furaldehyde to provide a range of pi-diverse 5-aryl-2-formylfuran derivatives is described. The method employs functionalized aryl halides and a catalytic amount of palladium(II) chloride under relatively mild conditions.
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