Ketone-DNA: A Versatile Postsynthetic DNA Decoration Platform
Organic Letters2001Vol. 3(25), pp. 3983–3986
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Abstract
[reaction: see text] A general strategy for the functional diversification of DNA oligonucleotides under physiological conditions was developed. We describe the synthesis of DNA molecules bearing ketone ports (ketone-DNA) and the efficient postsynthetic decoration of ketone-DNA with structurally diverse aminooxy compounds.
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