Facile Metal-Assisted Hydrolysis of a Urethane
Organic Letters2001Vol. 3(24), pp. 3895–3898
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Abstract
Kinetic studies demonstrate that it is possible to achieve large rate enhancements (2 x 10(4)) for the hydrolysis of a urethane group by using metal-bound water or hydroxide as the nucleophile. [reaction: see text]
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