Militarinone A, a Neurotrophic Pyridone Alkaloid from Paecilomyces militaris1
Organic Letters2001Vol. 4(2), pp. 197–199
Citations Over TimeTop 16% of 2001 papers
Abstract
[structure: see text] A new pyridone alkaloid, militarinone A (1), was isolated by bioassay-guided fractionation from the mycelium of the entomogenous fungus Paecilomyces militaris. Its structure was established by extensive spectroscopic analysis. The compound features an unprecedented side chain and a 1,4-substituted cyclohexyl moiety not previously encountered in microbial metabolites. Militarinone A had a pronounced neurotrophic effect in PC-12 cells at 10 microM concentrations.
Related Papers
- → Identification and taxonomy of some entomopathogenic Paecilomyces spp. (Ascomycota) isolates using rDNA-ITS Sequences(2006)85 cited
- → Identification and characterization of a special species of Paecilomyces(2012)13 cited
- Two New Records of Paecilomyces in China(2003)
- Infection of Paecilomyces farinosus on Pissodes punctatus(2007)
- Virulence Rejuvenescence of Paecilomyces farinosus and Forest Application Techniques(2008)