Directed Reduction of β-Amino Ketones to Syn or Anti 1,3-Amino Alcohol Derivatives
Organic Letters2002Vol. 4(18), pp. 3131–3134
Citations Over TimeTop 20% of 2002 papers
Abstract
[reaction: see text] The reduction of beta-amino ketones with samarium(II) iodide has been investigated. Either the syn or anti 1,3-amino alcohols can be obtained as the major product due to a divergence in selectivity with different N-protecting groups.
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