Synthesis of a Tricyclic Mescaline Analogue by Catalytic C−H Bond Activation
Organic Letters2003Vol. 5(8), pp. 1301–1303
Citations Over TimeTop 10% of 2003 papers
Abstract
[reaction: see text] A tetrahydrobis(benzofuran) mescaline analogue has been prepared in six steps and 38% overall yield from (4'-O-methyl)methyl gallate. The key step in this synthesis is a tandem cyclization reaction via directed C[bond]H activation followed by olefin insertion.