Enantiospecific First Total Synthesis and Assignment of Absolute Configuration of the Sesquiterpene (−)-Cucumin H
Organic Letters2003Vol. 5(13), pp. 2295–2298
Citations Over TimeTop 10% of 2003 papers
Abstract
The first total synthesis of the sesquiterpene (-)-cucumin H, a linear triquinane isolated from Macrocystidia cucumis, has been accomplished starting from (R)-limonene employing two different cyclopentannulation methodologies, which in addition to confirming the structure also established the absolute configuration of the natural product. [reaction: see text]
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