Unusual C25 Steroids Produced by a Sponge-Derived Penicillium citrinum
Organic Letters2003Vol. 5(23), pp. 4393–4396
Citations Over TimeTop 16% of 2003 papers
Taro Amagata, Akiko Amagata, Karen Tenney, Frederick A. Valeriote, Emil B. Lobkovsky, Jon Clardy, Phillip Crews
Abstract
[structure: see text] Structurally unique steroids, isocyclocitrinol A (1) and 22-acetylisocyclocitrinol A (2), were isolated from the extract of a saltwater culture of sponge-derived Penicilliun citrinum. The structures were established by analysis of 1D and 2D NMR data. The absolute structures were determined on the basis of X-ray structure analysis and application of modified Mosher's method. Furthermore, the structure of cyclocitrinol (3a) previously isolated from a terrestrial P. citrinum was revised as 3b. Compounds 1 and 2 showed weak antibacterial activity against Staphylococcus epidermidis and Enterococcus durans.
Related Papers
- → Citrinin produced using strains of Penicillium citrinum from Liupao tea(2019)20 cited
- → Production of Citrinin by Penicillium citrinum in Different Liquid Media(1977)6 cited
- Citrinin production by Penicillium citrinum NRRL 1841 and Penicilliun citrinum MTCC 2547 under laboratory conditions(2008)
- → LC-HRMS Profile of Chemical Compounds in Penicillium citrinum XT6 Extract(2023)1 cited
- → ИСПОЛЬЗОВAНИЕ ПОТЕНЦИAЛA СОЦИAЛЬНЫХ ПAРТНЕРОВ В ПОДГОТОВКЕ БУДУЩИХ ПЕДAГОГОВ(2024)