Facile N-Arylation of Amines and Sulfonamides
Organic Letters2003Vol. 5(24), pp. 4673–4675
Citations Over TimeTop 10% of 2003 papers
Abstract
[reaction: see text] A facile, transition-metal-free N-arylation procedure for amines and sulfonamides has been developed, which affords good to excellent yields of arylated products under very mild reaction conditions. A methoxy-substituted aryl triflate affords N-arylated products in high yields with excellent regioselectivity. This chemistry tolerates a variety of functional groups.
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