Facile O-Arylation of Phenols and Carboxylic Acids
Organic Letters2003Vol. 6(1), pp. 99–102
Citations Over TimeTop 10% of 2003 papers
Abstract
[reaction: see text] A facile, transition-metal-free O-arylation procedure for phenols and aromatic carboxylic acids has been developed that affords good to excellent yields of arylated products under very mild reaction conditions. A methoxy-substituted aryl triflate affords O-arylated products in high yields with excellent regioselectivity. This chemistry tolerates a variety of functional groups.
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