An Improved Synthesis of the “Miracle Nutrient” Coenzyme Q10
Organic Letters2005Vol. 7(19), pp. 4095–4097
Citations Over TimeTop 17% of 2005 papers
Abstract
[reaction: see text] A new route to the key coupling partner, chloromethylated CoQ0 (1), allows for direct formation of CoQ10 (3) via nickel-catalyzed cross-coupling with the side chain in the form of an in situ-derived vinyl alane (2).
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