Development of a Novel, Highly Efficient Halide-Catalyzed Sulfenylation of Indoles
Organic Letters2006Vol. 8(4), pp. 565–568
Citations Over TimeTop 10% of 2006 papers
Abstract
[reaction: see text] The reaction of a variety of indoles with N-thioalkyl- and N-thioarylphthalimides to produce 3-thioindoles is reported. Catalytic quantities of halide-containing salts are crucial to the success of this reaction. This highly efficient reaction provides sulfenylated indoles from bench-stable, readily available starting materials in good to excellent yields.
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