A Facile and Efficient Direct Aldol Addition of Simple Thioesters
Organic Letters2006Vol. 8(7), pp. 1503–1506
Citations Over TimeTop 10% of 2006 papers
Abstract
[reaction: see text] Simple thioesters undergo direct aldol addition to aldehydes in the presence of MgBr(2).OEt(2) and i-Pr(2)NEt using untreated, reagent-grade CH(2)Cl(2) under atmospheric conditions. The reactions proceed extremely rapidly and in excellent yield.
Related Papers
- → First Catalytic Aldol-Transfer Reaction via Aluminum Enolates: A New Way To Generate Aldol Adducts of Aldehydes from Aldol Adducts of Ketones(2000)30 cited
- → Synthesis of the C1−C12 Fragment of the Tedanolides. Aldol−Non-Aldol Aldol Approach(2007)19 cited
- → 6.5 C–C Bond Formation: Aldol Reaction with Non-Proline Derivatives(2012)1 cited
- → Studies in Organocatalysts Synthesis for Direct Aldol Reaction(2013)
- High Enantioselective Organocatalytic Asymmetric Direct Aldol Reactions of Aldehydes with Long-Chain Aliphatic Ketones(2009)