Novel and Efficient Synthesis of Iminocoumarins via Copper-Catalyzed Multicomponent Reaction
Organic Letters2006Vol. 8(20), pp. 4517–4520
Citations Over TimeTop 10% of 2006 papers
Abstract
A variety of substituted iminocoumarins are prepared in good to excellent yields via a copper-catalyzed multicomponenet reaction of sulfonyl azides, terminal alkynes, and salicylaldehydes or o-hydroxylacetophenones. The method is general, mild, versatile, and efficient. A plausible mechanism for the domino process is proposed.
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