Gold(I)-Catalyzed Tandem Cyclization Approach to Tetracyclic Indolines
Organic Letters2010Vol. 12(7), pp. 1448–1451
Citations Over TimeTop 10% of 2010 papers
Abstract
Two highly stereoselective cationic gold(I)-catalyzed tandem cyclization reactions of alkynylindoles are described. These reactions demonstrated a novel and general strategy to rapidly construct highly functionalized polycyclic indolines. This approach was successfully employed for a formal synthesis of the akuammiline alkaloid minfiensine.
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