TBHP/I2-Mediated Domino Oxidative Cyclization for One-Pot Synthesis of Polysubstituted Oxazoles
Organic Letters2010Vol. 12(23), pp. 5561–5563
Citations Over TimeTop 1% of 2010 papers
Abstract
A facile type of one-pot, transition-metal-free domino process was developed for the synthesis of oxazoles. Thus, a variety of polysubstituted oxazoles were easily synthesized via t-BuOOH/I(2)-mediated domino oxidative cyclization from readily available starting materials under mild conditions.
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