Asymmetric Synthesis of Tertiary Benzylic Alcohols
Organic Letters2010Vol. 13(2), pp. 184–187
Citations Over TimeTop 25% of 2010 papers
Abstract
Vinyl, aryl, and alkynyl organometallics add to ketones containing a stereogenic sulfoxide. Tertiary alcohols are generated in diastereomerically and enantiomerically pure form. Reductive lithiation converts the sulfoxide into a variety of useful functional groups.
Related Papers
- → Recent Advances in the Transition‐Metal‐Catalyzed Enantioselective Synthesis of Silicon‐Stereogenic Organosilanes(2015)126 cited
- → Enantioselective Organocatalyzed Formal [4+2] Cycloaddition of Ketimines with Allenoates: Easy Access to a Tetrahydropyridine Framework with a Chiral Tetrasubstituted Stereogenic Carbon Center(2014)59 cited
- → Enantioselective Formation of Cyano‐Bearing All‐Carbon Quaternary Stereocenters: Desymmetrization by Copper‐Catalyzed N‐Arylation(2014)13 cited
- → Organocatalytic Enantioselective Synthesis of P‐Stereogenic Chiral Oxazaphospholidines(2016)26 cited
- → Catalytic Asymmetric Synthesis of Silicon-Stereogenic Compounds by Enantioselective Desymmetrization of Prochiral Tetraorganosilanes(2018)19 cited