Asymmetric Organocatalytic Double-Conjugate Addition of Malononitrile to Dienones: Efficient Synthesis of Optically Active Cyclohexanones
Organic Letters2010Vol. 13(3), pp. 374–377
Citations Over TimeTop 10% of 2010 papers
Abstract
9-Amino-9-deoxyepiquinine efficiently catalyzed the double-conjugate addition of malononitrile to dienones. A number of 1,1,2,6-tetrasubstituted cyclohexanones were prepared in good yields, diastereoselectivities, and excellent enantioselectivities.
Related Papers
- → New Applications of Malononitrile in Organic Chemistry - Part I(1978)155 cited
- → Michael Addition of Malononitrile to α‐Acetylcinnamamides(1993)35 cited
- → A novel ratiometric fluorescent chemosensor for detecting malononitrile and application assisted with smartphone(2021)13 cited
- Recent Advance on Malononitrile Derivatives with Agricultural Activity(2010)
- Recent advance on application and synthesis of malononitrile derivatives(2015)