Copper(I) 1,2,3-Triazol-5-ylidene Complexes as Efficient Catalysts for Click Reactions of Azides with Alkynes

Citations Over TimeTop 1% of 2011 papers

Abstract

Complexes of copper with 1,4-diphenyl, 1,4-dimesityl, and 1-(2,6-diisopropylphenyl)-4-(3,5-xylyl)-1,2,3-triazol-5-ylidene (abnormal NHC = N-heterocyclic carbene) were prepared by consecutive treatment of the corresponding azolium salts with silver oxide and copper chloride. The new CuCl(aNHC) complexes efficiently catalyzed click reactions of azides with alkynes to give 1,4-substituted 1,2,3-triazoles in excellent yields at room temperature with short reaction times. CuCl(TPh) was particularly effective for the reaction between sterically hindered azides and alkynes.

Related Papers

• → Ion recognition by 1,2,3‐triazole moieties synthesized via “click chemistry”(2022)39 cited
• → Click-assembling triazole membrane on copper surface via one-step or two-steps and their corrosion inhibition performance(2017)28 cited
• → Facile synthesis of 1,2,3-triazole analogs of SGLT2 inhibitors by ‘click chemistry’(2011)33 cited
• → 1,2,3-Triazole Ferrocenyldendrimers Through Click Chemistry Approach and their Optical and Electrochemical Properties(2012)10 cited
• → Click Chemistry Approach to Fluorescence-Based Polybinaphthyls Incorporating a Triazole Moiety for Hg²+ Recognition(2010)7 cited